Opportunity Information: Apply for W81XWH 19 OCRP CDA

The DoD Ovarian Cancer Research Program (OCRP) Clinical Development Award (Funding Opportunity Number W81XWH-19-OCRP-CDA) is a Department of Defense funding opportunity designed to push ovarian cancer innovations past the preclinical stage and into real clinical use as quickly as possible. It focuses on translating already-promising discoveries into medical products and technologies that can meaningfully affect patient care in the near term. The intent is not to generate early exploratory biology in the lab, but to accelerate the clinical introduction of practical tools that directly address ovarian cancer biology, with an emphasis on measurable, near-term clinical impact.

This award supports development work tied to clinical applications across the full spectrum of patient need, including prevention, detection, diagnosis, treatment, and quality of life improvements. The central expectation is that applicants have already established proof of concept for the proposed product or have a prototype or preliminary version in hand. In other words, the application should not be built around the question of whether an idea might work in principle; it should be built around the plan to refine, validate, and move an innovation into early clinical settings where it can begin to show clinical value.

A key restriction is that animal preclinical studies are not allowed under this mechanism, reflecting the program's emphasis on readiness for clinical translation. Instead, the program allows small-scale clinical trials, specifically Phase 0 and Phase 1 studies, as well as projects that enrich or strengthen a clinical trial (for example, efforts that improve patient selection, biomarker validation, assay performance, endpoint development, or other trial-enabling components). Projects that are related to, associated with, or leverage ongoing or completed clinical trials are also permitted, which encourages applicants to build on existing clinical infrastructure and datasets rather than starting from scratch.

Applicants are required to provide relevant supporting data to justify the study rationale, and those data can be either published or unpublished. This requirement signals that proposals need a strong evidence base demonstrating feasibility and potential utility, consistent with a program that expects translation-ready concepts rather than speculative early research. Overall, the award is structured for teams that are prepared to take a developed candidate product or technology and do the work needed to make it clinically actionable in ovarian cancer.

Administratively, this is a discretionary opportunity offered by the Department of Defense, Department of the Army, administered through USAMRAA. It may be awarded as either a grant or a cooperative agreement, and it falls under CFDA 12.420 (research and development). Eligibility is listed as unrestricted, meaning it is open to a wide range of entity types unless further limits are specified in the full announcement. The opportunity was originally posted March 1, 2019, with an original closing date of July 31, 2019, and it anticipated making about four awards. The listing shows an award ceiling of 0, which typically indicates that applicants must refer to the full funding announcement for specific budget guidance or that the ceiling is not represented in the summary field.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Ovarian Cancer Clinical Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Mar 01, 2019.
  • Applicants must submit their applications by Jul 31, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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