Opportunity Information: Apply for RFA EB 23 007

This funding opportunity, RFA-EB-23-007, is a National Institutes of Health (NIH) Notice of Funding Opportunity designed to support the NIH Blueprint for Neuroscience Research NeuroImaging Tools and Resources Collaboratory. Its central aim is to strengthen collaborative work in neuroimaging informatics by sustaining and advancing shared tools, resources, and coordination activities that help the neuroscience community develop, manage, analyze, and disseminate neuroimaging data more effectively. The award mechanism is an R24 grant, and it is explicitly labeled "Clinical Trial Not Allowed," meaning the funded scope is intended for resource, infrastructure, and collaborative informatics support rather than running interventional clinical studies.

A defining feature of this NOFO is that it is a single-source, limited competition. Eligibility is restricted primarily to the U24 awardees and subawardees funded under the earlier initiative RFA-EB-16-002. In other words, the opportunity is structured to continue or transition an existing collaboratory effort rather than open a broad, new competition to the entire research community. Even with that restriction, the listing also notes categories of other eligible applicant types that NIH commonly includes, such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. The general eligible applicant pool described in the source data also spans state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized tribes and other tribal organizations; public housing/Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. Practically, however, the core limitation to prior U24 awardees/subawardees is the key gatekeeper for who can actually compete.

Foreign participation is handled in a nuanced way. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. At the same time, "foreign components" as defined by the NIH Grants Policy Statement are allowed, which typically means a U.S. applicant may include certain activities performed outside the U.S. when they are scientifically justified and properly structured under NIH policy, even though a foreign organization cannot serve as the prime applicant.

Administratively, this is a discretionary grant program run by NIH, falling under the broad activity areas of education, environment, health, income security, and social services as reflected in the government-wide categorization. The CFDA/assistance listing numbers associated with the opportunity include 93.113, 93.121, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, and 93.867, indicating that multiple NIH institutes or program areas may be tied to the Blueprint and neuroimaging-related funding streams. The posting indicates an award ceiling of $700,000, with the original closing date listed as September 26, 2023, and a creation date of July 13, 2023. The expected number of awards is not specified in the provided source data.

In plain terms, the opportunity is aimed at keeping a specialized neuroimaging informatics collaboratory functioning and productive, emphasizing shared tools and resources and enabling collaboration across the neuroscience neuroimaging ecosystem, while limiting who can apply to teams already funded in the prior U24 program lineage and keeping the work non-clinical-trial in nature.

  • The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Single Source: NIH Blueprint for Neuroscience Research: NeuroImaging Tools and Resources Collaboratory (R24 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867.
  • This funding opportunity was created on 2023-07-13.
  • Applicants must submit their applications by 2023-09-26. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $700,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for RFA EB 23 007

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Frequently Asked Questions (FAQs): NIH RFA-EB-23-007 (NeuroImaging Tools and Resources Collaboratory)

What is the funding opportunity number and title?

This opportunity is NIH Notice of Funding Opportunity (NOFO) RFA-EB-23-007. It is designed to support the NIH Blueprint for Neuroscience Research NeuroImaging Tools and Resources Collaboratory.

What is the main goal of RFA-EB-23-007?

The central aim is to strengthen collaborative work in neuroimaging informatics by sustaining and advancing shared tools, resources, and coordination activities that help the neuroscience community develop, manage, analyze, and disseminate neuroimaging data more effectively.

What type of grant mechanism is used for this opportunity?

The award mechanism is an R24 grant. Based on the description provided, the R24 is being used to support resource/infrastructure-style activities and collaborative coordination for neuroimaging informatics.

Are clinical trials allowed under this NOFO?

No. The opportunity is explicitly labeled "Clinical Trial Not Allowed". The funded scope is intended for resource, infrastructure, and collaborative informatics support rather than running interventional clinical studies.

Is this an open competition?

No. This is described as a single-source, limited competition. It is structured to continue or transition an existing collaboratory effort rather than run a broad, open competition.

Who is actually eligible to apply (practically speaking)?

Eligibility is restricted primarily to the U24 awardees and subawardees funded under the earlier initiative RFA-EB-16-002. In practical terms, this prior participation is the key gatekeeper for who can compete for this R24.

Why does the listing mention many other eligible applicant categories if competition is limited?

The source information includes a broad set of applicant categories NIH commonly lists (for example, various institution types and government entities). However, the defining feature of this NOFO is the limited competition tied to the earlier RFA-EB-16-002 U24 lineage, which overrides the general breadth for most would-be applicants.

What types of organizations are referenced as eligible applicant types in the listing?

The provided information notes that NIH commonly includes categories such as:

  • Alaska Native and Native Hawaiian Serving Institutions
  • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Hispanic-serving Institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Eligible federal agencies
  • Faith-based or community-based organizations
  • Regional organizations
  • U.S. territories or possessions

The general eligible applicant pool described also spans:

  • State, county, city/township, and special district governments
  • Independent school districts
  • Public and private institutions of higher education
  • Federally recognized tribes and other tribal organizations
  • Public housing/Indian housing authorities
  • Nonprofits with or without 501(c)(3) status
  • For-profit organizations (other than small businesses)
  • Small businesses

Even so, the limited-competition restriction to prior U24 awardees/subawardees remains the central eligibility constraint described.

Can a foreign organization apply as the prime applicant?

No. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization.

Can a non-domestic component of a U.S. organization apply?

No. The information provided states that non-domestic components of U.S. organizations are not eligible to apply.

Are any international activities allowed at all?

Yes, in a limited/structured way. The information provided states that "foreign components" (as defined by the NIH Grants Policy Statement) are allowed. This generally means a U.S. applicant may include certain activities performed outside the U.S. when justified and properly structured under NIH policy, even though a foreign organization cannot be the prime applicant.

Which NIH initiative does this opportunity support?

This NOFO supports the NIH Blueprint for Neuroscience Research, specifically focused on a NeuroImaging Tools and Resources Collaboratory and neuroimaging informatics coordination.

What kinds of activities are emphasized by the NOFO?

Based on the description provided, the emphasis is on:

  • Sustaining and advancing shared neuroimaging informatics tools and resources
  • Coordination activities that enable collaboration
  • Supporting the development, management, analysis, and dissemination of neuroimaging data

Is this funding meant to start a new collaboratory or continue an existing one?

It is structured to continue or transition an existing collaboratory effort, rather than start a brand-new, broadly competed program, as shown by the limited competition restricted to prior U24 awardees/subawardees under RFA-EB-16-002.

What is the maximum award amount (ceiling) listed?

The posting indicates an award ceiling of $700,000.

How many awards will NIH make under this opportunity?

The expected number of awards is not specified in the provided source data.

What are the key dates mentioned in the source information?

The source information includes:

  • Creation date: July 13, 2023
  • Original closing date: September 26, 2023

What agency is administering this funding opportunity?

This is a discretionary grant program administered by the National Institutes of Health (NIH).

What broad activity areas are associated with this grant listing?

The opportunity is categorized under broad government-wide activity areas including education, environment, health, income security, and social services, as reflected in the provided categorization.

What Assistance Listing (CFDA) numbers are associated with this opportunity?

The source information associates the opportunity with the following Assistance Listing/CFDA numbers:

  • 93.113
  • 93.121
  • 93.213
  • 93.242
  • 93.273
  • 93.279
  • 93.286
  • 93.853
  • 93.865
  • 93.866
  • 93.867

As described, these indicate multiple NIH institutes or program areas may be tied to the Blueprint and neuroimaging-related funding streams.

Does the opportunity focus on neuroimaging data sharing and dissemination?

Yes. A stated purpose is to help the neuroscience community more effectively develop, manage, analyze, and disseminate neuroimaging data, which implies a strong focus on shared resources and coordinated approaches to data handling.

If our organization was not part of the earlier RFA-EB-16-002 U24 effort, should we expect to be competitive?

Based on the information provided, the competition is limited primarily to U24 awardees and subawardees under RFA-EB-16-002. If an organization was not part of that lineage, the opportunity is not described as broadly competitive for new entrants.

What is the simplest way to describe this opportunity?

It is an NIH R24 funding opportunity meant to keep a specialized neuroimaging informatics collaboratory functioning and productive by supporting shared tools/resources and collaboration, while restricting eligibility mainly to prior U24 teams and excluding clinical trials.

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