Opportunity Information: Apply for USDA APHIS 10025 VSSP0000 25 0015

The HPAI Poultry Innovation Grand Challenge is a discretionary USDA funding opportunity run through the Animal and Plant Health Inspection Service (APHIS) aimed at accelerating practical, high-impact solutions to highly pathogenic avian influenza (HPAI). The program sits under USDA's broader, newer strategy to curb avian flu, protect the U.S. poultry sector, and help lower egg prices, as outlined in the Secretary of Agriculture's February 26, 2025 press release announcing up to $1 billion in efforts to combat avian flu and reduce egg prices. In plain terms, this grant is meant to push forward innovations that can reduce outbreaks, limit losses, and strengthen the industry's ability to prevent, detect, and respond to HPAI.

APHIS plans to make available up to $100,000,000 total for projects that align with the specific funding priorities listed in Appendix 1 of the full announcement. While the total pool is large, USDA is explicit that there is no guarantee any particular application will be funded, and the agency is not obligated to make awards simply because proposals are submitted. The focus is on projects that clearly map to the announced priorities and can demonstrate strong technical merit, feasibility, and potential for real-world impact.

Awards will be made primarily through cooperative agreements (and via interagency agreements when the recipient is a federal agency). A cooperative agreement matters because it signals that APHIS may have substantial involvement during the project, meaning the agency can play an active role in supporting, guiding, or coordinating aspects of the work to help ensure the project meets its goals and aligns with USDA's strategy. This is not just a hands-off grant; applicants should expect a more collaborative federal partner compared to many standard assistance awards.

The selection process is competitive and merit-based. Proposals are reviewed and scored under a structured review process described in Section 6 of the full announcement, and funding is intended for the highest-quality applications. The number of awards is not fixed and will depend on how many strong proposals are submitted. Even with positive reviews, final award decisions remain at USDA's discretion, which is typical for federal competitive funding.

Applicants should also be prepared for budget negotiation. Based on reviewer feedback, APHIS may offer an award amount that is lower than what was requested. If that happens, the applicant can either accept or decline. If they accept the reduced amount, they will be asked to submit a revised application that addresses reviewer concerns and adjusts the scope, milestones, and budget to match the final award level, with APHIS providing guidance on what revisions are needed.

Eligibility is broad and includes a wide mix of organizations involved in poultry production, animal health, research, emergency response, and innovation. Eligible applicants include for-profit organizations (including small businesses), colleges and universities (including university research foundations), poultry producer organizations with a direct or significant economic interest in poultry production, veterinary organizations or specialty boards recognized by the American Veterinary Medical Association, federal agencies, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education), state departments of agriculture, and state emergency agencies. Non-U.S. entities and non-U.S. components of U.S. organizations can apply, but they should anticipate additional review and approval steps.

Key administrative details from the listing include the opportunity title (HPAI Poultry Innovation Grand Challenge), funding opportunity number (USDA APHIS 10025 VSSP0000 25 0015), assistance type (cooperative agreement), activity category (agriculture), and CFDA/Assistance Listing number (10.025). The original application closing date shown is May 19, 2025, and the opportunity was created March 19, 2025.

  • The Animal and Plant Health Inspection Service in the agriculture sector is offering a public funding opportunity titled "HPAI Poultry Innovation Grand Challenge" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 10.025.
  • This funding opportunity was created on 2025-03-19.
  • Applicants must submit their applications by 2025-05-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others.
Apply for USDA APHIS 10025 VSSP0000 25 0015

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